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New PublicationsMYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention

A new study from the group of Moritz Mall revealed how MYT1L mutation causes both developmental and postmitotic neurological defects. Acute intervention can normalise resulting electrophysiological and behavioural phenotypes in adulthood.

Graphical Abstract for Weigel et al 2023